London Wasps secured a 29-19 bonus point Aviva Premiership victory over London Welsh in the two teams' first ever league meeting.
London Welsh were forced to make a change to their starting line up ahead of the match as Ed Jackson failed a fitness test.
Jackson's place at number eight was taken by Alfie To'oala, with Mike Denbee then being named in the replacements.
On the bench, Gordon Ross and Greg Bateman replaced Joe Ajuwa and Arthur Joly respectively.
London Wasps were also forced into changes as James Haskell had to be replaced due to illness and his number seven shirt was taken by Jonathan Poff with Sam Jones taking Poff’s place on the bench.
Wasps opened up a 16-6 lead at half-time through Christian Wade and Tom Varndell tries, while Nicky Robinson and Lee Thomas added points from the boot.
Welsh's first half response came through Gavin Henson's two three-pointers before Wade and Varndell went over again in the second period.
Phil Mackenzie and Franck Montanella touched down for the visitors and Gordon Ross kicked a late penalty, but it wasn't enough as Thomas prevented the opposition from gaining a losing bonus-point.
Against most people's expectations, Welsh sit comfortably above the 12th-placed side at the moment. However, they were facing a rejuvenated Wasps' outfit who could probably consider themselves unlucky to be in the bottom half of the table.
And the hosts showed the quality that they possess when Wade finished off a fine backline move. That lead was extended to 8-0 through a Robinson penalty before Henson reduced the arrears with one of his own.
In their wingers, the High Wycombe side have two of the most potent try-scorers in the league and that was evident once more when Varndell scampered over from long range.
But the visitors continued to battle and their fly-half's second three-pointer got them to within seven points.
It was Wasps who continued to control proceedings, though, and Thomas added a drop goal to give Dai Young's team a relatively comfortable 16-6 cushion at the interval.
The hosts were soon into their stride in the second half when Wade scored yet another superb touchdown, beating several defenders on his way to the line.
Mackenzie finished off a fine counter-attack for the Oxford-based outfit's first try, but Wasps kept their opponents at arm's length when Varndell crossed the whitewash for the second time.
Montanella then went over and Ross slotted a penalty to get the visitors to within seven, but Thomas kicked a three-pointer late on to seal the victory for the former champions.
Final Score London Wasps (16) 29 London Welsh (6) 19
Tries: Wade 2, Varndell 2
Pens: Robinson, Thomas
Drop Goals: Lee Thomas
Tries: Mackenzie, Montanella
Pens: Henson 2, Ross
Referee: Nigel Owens (WRU, 6th Premiership game)
Assistant Referees: Nigel Carrick, Andrew Watson.
15. Hugo Southwell , 14. Tom Varndell , 13. Andrea Masi , 12. Lee Thomas , 11. Christian Wade , 10. Nick Robinson , 9. Joe Simpson , 1. Tim Payne , 2. Tom Lindsay , 3. Zak Taulafo , 4. Joe Launchbury , 5. Marco Wentzel , 6. Ashley Johnson , 7. Jonathan Poff , 8. Billy Vunipola
Replacements:16. T Rhys Thomas , 17. Phil Swainston , 18. Fabio Staibano , 19. James Cannon , 20. Sam Jones , 21. Charlie Davies , 22. Tommy Bell , 23. Elliot Daly
15. Tom Voyce, 14. Phil MacKenzie, 13. Sonny Parker, 12. Seb Jewell, 11. Nick Scott, 10. Gavin Henson, 9. Tyson Keats, 1. Franck Montanella, 2. Neil Briggs, 3. Paulica Ion, 4. Martin Purdy , 5. Matt Corker, 6. Jonathan Mills (c) 7. Michael Hills, 8. Alfie To'oala.
Replacements: 16. Dan George, 17. Tom Bristow, 18. Greg Bateman, 19. Kirill Kulemin, Mike Denbee, 21. Nick Runciman, 22. Gordon Ross, 23. James Lewis.