Griquas outgoing coach Pote Human has given Currie Cup debuts to two players for their match against the Blue Bulls in Kimberley on Saturday.
Props Ewald van der Westhuizen and Brendon Pitzer, who both played Varsity Cup rugby earlier this year, have both been included in the Griquas match day 22.
Van der Westhuizen, who played for the University of Johannesburg in this year's student competition, has been included at tight head prop in the absence of injured stalwart Nick Schonert.
Pitzer, who played for Maties, could make an impact from the replacement bench against the visitors.
"Both Ewald and Brendon have slotted into the structures nicely and we are confident that they will do their share to help the team against the Blue Bulls," Human said.
"The younger players like Carel Greeff and RJ Liebenberg have shown what they are capable of, if given the chance, so we are looking forward to the impact the new youngsters will make."
Human has made a number of changes to his backline with scrumhalf Marnus Hugo coming into the side in place of Jacques Coetzee.
Veteran centre JP Nel also gets a start in place of Jean Stemmet, who has been relegated to the bench. Richard Lawson comes in at wing as a replacement for Nico Scheepers who suffered a hamstring injury earlier in the week.
"Injuries keep on interrupting us, but we will never use it as an excuse.
"We still firmly believe that we can reach the knock-out stages if we beat the Bulls.
"The team is motivated and we are confident of a good performance against the visitors."
Gouws Prinsloo, Richard Lawson, JP Nel, Howard Mnisi, Rocco Jansen, Francois Brummer, Marnus Hugo, Leon Karemaker, Burger Schoeman, Marnus Schoeman, Jaco Nepgen, Rory Arnold, Ewald van der Westhuizen, Ryno Barnes (captain), Steph Roberts
Replacements: Matt Dobson, Brendon Pitzer, Patrick O'Brien, RJ Liebenberg, Jacques Coetzee, Du Randt Gerber, Jean Stemmet.