Ireland flyhalf Jonny Sexton has been ruled out of their final Six Nations match against Italy after a training ground injury.
Sexton recovered from the hamstring injury that had kept him out and was named in the starting XV earlier today.
However during Thursday's trainng session Sexton went over on his foot in training.
A scan has confirmed that he has torn a tendon in his left foot and has therefore been ruled out this weekend.
Paddy Jackson will start the game, earning his 3rd cap.
Ian Madigan, who made his debut against France last weekend,comes in to the replacements.
Rob Kearney; Craig Gilroy, Brian O'Driscoll, Luke Marshall, Keith Earls; Paddy Jackson, Conor Murray; Jamie Heaslip, Sean O'Brien, Peter O'Mahoney; Donnacha Ryan, Mike McCarthy; Mike Ross, Rory Best, Cian Healy.
Replacements: Sean Cronin, David Kilcoyne, Stephen Archer, Devin Toner, Iain Henderson, Paul Marshall, Ian Madigan, Luke Fitzgerald.