The Sharks have named their team to face the Brumbies with Keegan Daniel in the starting line up and the surprise naming of Jacques Botes on the bench.
The Sharks revealed earlier this week that they had lost Botes for up to a month but his early diagnosis was incorrect as it was an old injury.
"Jacques Botes was initially diagnosed with a cracked wrist, but on later examination we discovered that he has had it for a long time, that it was a previous injury, it just shows that the older you get, the tougher you get," said Sharks coach John Plumtree
"It's not a new injury but he's alright and that's good news for the team."
Botes will come off the bench while captain Keegan Daniel is named in the side for the first time this season after he was injured in the pre-season clash with the Leopards.
Plumtree has made two changes in the backline.
"Charl McLeod hasn't had an opportunity, he's been really looking forward to having one and I think it's a good time to re-introduce him. He'll be looking forward to a good game.
"It's the same with Odwa Ndungane, he hadn't started a game yet so we wanted to give him an opportunity at some point, it's a big game this week."
The Sharks had named an unchanged team in all three of their previous matches but were forced to make some changes this week.
"We've had some enforced changes and a couple of rotational changes amongst the backs, we have a good squad and both those backs deserve a start, it's up to them to take the opportunity," said Plumtree.
15. Louis Ludik , 14. Odwa Ndungane , 13. Paul Jordaan , 12. Francois Steyn , 11. JP Pietersen , 10. Patrick Lambie , 9. Charl McLeod , 8. Ryan Kankowski , 7. Keegan Daniel (C) , 6. Marcell Coetzee , 5. Franco van der Merwe , 4. Anton Bresler , 3. Jannie du Plessis , 2. Craig Burden , 1. Tendai Mtawarira
Replacements , 16. Kyle Cooper , 17. Wiehahn Herbst , 18. Pieter-Steph du Toit , 19. Jacques Botes , 20. Cobus Reinach , 21. Meyer Bosman , 22. Lwazi Mvovo