Scotland have suffered a blow ahead of their Autum International against South Africa at Murrayfield on Saturday as Flanker Alasdair Strokosch has been ruled out.
Strokosch was ruled out through injury and will be replaced in a recast Scotland back-row by 26-year-old John Barclay (Glasgow Warriors) who will be winning his 40th cap.
Barclay will don the openside shirt, the position in which he won Man of the Match in the corresponding fixture two years ago, with Kelly Brown reverting to blindside. David Denton remains at No 8.
Drafted on to the Scotland bench is the uncapped 22-year-old Edinburgh Rugby back-row forward Stuart McInally, who has captained Scotland at every age-grade and represented Scotland 7s and Scotland A.
Scotland team doctor James Robson said: "Alasdair suffered a minor calf strain in training this week and while we were hopeful it would settle in time we believe his recovery has not been sufficient to warrant risking a partially fit player."
Scotland head coach Andy Robinson said: "We wish 'Stroker' a speedy recovery. John is an experienced campaigner, while Stuart was with us on the summer tour and is raring to go."